Our review of the scientific
research which has been done on the ingredients in this product reveals
the following results were obtained with these nutrients in regard to
the above-mentioned factors.
A.
LOWERING HIGH CHOLESTEROL
As almost everyone knows
these days, high levels of fat in the blood (as measured by triglycerides
and cholesterol) is one of the major indicators of cardiovascular problems.
However, what most people do not know is that a large number of nutrients
have been scientifically shown to lower cholesterol to normal levels.
These nutrients all play a natural role in the body's handling of fats.
However, due to a variety of reasons ranging from genetic differences
and unbalanced diets to growing older, some people need more of these
nutrients than they can get from their food. Supplementing with these
nutrients has often produced amazing results.
MARINE LIPIDS
One of the most exciting development is the recent discovery that nutrients
found in certain fish oils discovery that nutrients found in certain
fish oils can have a major benefit in lowering cholesterol. These nutrients
are known as Omega 3 fatty acids. Two of these, EPS (ecosapentaenoic
acid) and DHA (docosahexaenoic acid) have proven to be especially beneficial.
It was discovered that Greenland Eskimos and Japanese fishing village
residents had very low levels of triglycerides and cholesterol. They
almost never had heart attacks. Their blood contained high amounts
of the EPA and DHA from their diet, high in cold-water fish Scientists
found these fatty acids were very lipotropic- that is, they had the
ability to dissolve and disperse cholesterol. Especially the dangerous
LDL form, while protecting the benificial HDL form of cholesterol. Several
groups of doctors have given these marine lipids to group of individuals
with high cholesterol, and in each case there was a very significant
improvement. At the University of Oregon, extensive studies have been
going of for years with regard to marine lipids. Drs. Harris and Connors,
along with others physicians, have found that when marine lipids
are given as a nutritional supplement on a daily basis, there is a beneficial
decline in both triglycerides and the harmful and dangerous LDL cholesterol.
Dr. Connor has commented, "The higher these levels (cholesterol and
triglycerides) are when the fish oil program started, usually the greater
the fall."
VITAMINS TO LOWER CHOLESTEROL
One of the most discouraging things to heart patients is to cut out
all their favorite foods because they contain cholesterol, only to find
out after months of dieting that their cholesterol had hardly declined.
At the University of Illinois, Dr. F.A. Kummerow tested a large number
of patients on cholesterol restricted diets. He found only 10% of
th cholesterol in the blood is contributed by cholesterol in the diet.
A much more effective way to control cholesterol is to give supplements
of nutrients which are required by the liver for proper metabolism of
carbohydrates, fats, and cholesterol.
Among the most significant of these is a little known B vitamin called
inositol. Without sufficient quantities of inositol, the liver is unable
to efficiently convert fats and carbohydrates to energy- thus they end
up as fat in the blood. Drs W.C.Felch and L.B. Dotti took a group of
diabetic patients with elevated triglycerides and cholesterol levels
and gave them insitol supplements. Within a few weeks these patients
had their triglycerides and cholesterol return to normal. Reporting
in the American Heart Journal, Drs. Leinwand and Moore describrd how
they gave supplements of inositol to a group of heart patients with
elevated cholesterol and triglyceride levels.
In a few weeks on inositol supplements, there was a substantial drop
in these elevated levels to normal ranges. Choline is another little-known
B vitamin that works with insitol in the liver to control fat metabolism.
Drs. Morrison and Gonzales gave supplements of choline to a group of
115 cardiovascular patients, and placebo to a matched group of 115 others.
There was a substantial decline in the level of triglycerides and cholesterol,
but only in those receiving the choline. However, most importantly,
over the next three years there was a 60% decline in the death rate
for those taking the choline- compared to the placebo group.
Scientists now know the importance of these vitamins to the liver in
manufacturing lecithin- a very powerful fat dissolving detergent which
reduces blood fat levels. As far back as 1958, Dr. T.D. Labeski had
demonstrated that by supplementing the diet with both choline and inositol,
the blood level of lecithin would rise followed by a decline in triglycerides
and cholesterol. In just two months, patients who had just had heart
attacks had their cholesterol and triglycerides brought to normal using
only choline and inositol.
METHIONINE, VITAMIN B-6
AND MAGNESIUM
It is well known among scientists that methionine is essential to proper
fat metabolism in the liver. One reason for this that it converted to
choline and then lecithin. Drs. Mann and Andrus of Harvard University
demonstrated the importance of methionine by feeding these monkeys a
diet that was complete in all respects except in the amino acid methionine.
The monkeys soon developed high cholesterol and aherosclerosis. However,
methionine cannot be adequately converted to choline or lecithin unless
there is a sufficient amount of vitamin B-6. research by Dr. K. McCully
at Harvard Medical School established that without adequate vitamin
B-6, methionine would be converted to homocysteine. This is a powerfull
free radical which damages arterial walls, resulting in plaque formation.
Many scientists feel that most Americans are very deficient in this
important nutrient. This may be a major cause in the formation of atherosclerosis.
However, the liver still cannot make lecithin unless there is also enough
magnesium present. Magnesium is essential for the utilization of amino
acids and the lowering of blood lipid levels. Yet when they were given
magnesium supplements, within just one month many of these elevated
cholesterol levels fell dramatically. In 1984 Dr. W. H. Davis and
associates gave magnesium supplements to a group of men with abnormally
low levels of the protective HDL cholesterol. Within weeks this magnesium
supplement had elevated the protective HDL level.
CALCIUM AND CHROMIUM
In 1972 Dr. M. L. Biembaum and associates gave large groups of patients
with elevated serum (blood) cholesterol a daily supplement of calcium.
After a year of calcium supplements their serum cholesterol fell by
an average of 25%. Chromium is another mineral which has shown the ability
to lower serum cholesterol. In 1981 Drs. Railes and Albrink gave daily
200 mcg. supplements of chromium to patients with elevated serum triglycerides
and cholesterol. Their elevated levels soon returned to normal along
with an increase in the beneficial and protective HDL cholesterol, and
an improvement in their tolerance to glucose.
NIACIN AND VITAMIN C
In 1975 the Coronary Drug Project Research Group of the American Medical
Association reported that one of the most effective agents for lowering
cholesterol was the vitamin B niacin. They found that it also reduced
the rate of reoccurring heart attacks by 29%. Dr. Grundy and associates
reported the results of their research with niacin in 1981. They found
niacin produced a 22% reduction of serum cholesterol and a 52% reduction
in triglycerides. In 1976 Drs. Turly, West, and Horton demonstrated
that when Vitamin C is present in the blood serum it stimulates the
release and activation of plasma lipoprotein lipase which promotes
the breakdown of serum triglycerides. Research in 1979 by Dr. Emil Ginter
and associates has revealed that a liver enzyme which is responsible
for the conversion of excess blood cholesterol to bile for elimination,
is vitamin C dependent. Without adequate vitamin C in the liver,
cholesterol soon accumulates in the blood. These discoveries explain
why by 1970 three different research groups had found that the serum
cholesterol level goes up and down with the intake of vitamin C. In
1971 Dr. C.R. Spittle, a Vitamin C researcher, wrote: "Atherosclerosis
is a long-term deficiency of Vitamin C which permits cholesterol to
build in the arterial system and results in changes in other fractions
of fats." Nobel Prize winning scientists, Dr. Linus Pauling tells how
changes were reversed. "...a high level of vitamin C increases the amount
of high density and decreases the amount of low density lipoprotein
cholesterol. Both of these changes help to protect against cardiovascular
disease."
GARLIC AND GINGER
Although revered by grandmothers from the "old country" for years, it
was not until 1977 that Drs. Bordia, Josh, and Sanadhya scientifically
demonstrated that daily garlic intake lowers the harmful LDL cholesterol
and triglycerides, while elevating the beneficial and protective HDL
cholesterol. In 1978 Dr. S Gujaral and associates found that the old-fashioned
herb Ginger is very effective in lowering serum cholesterol if taken
on a daily basis.
L-CARNITINE
One of the most exciting discoveries in the area of improving cardiovascular
health from a nutritional point of view is L-Carnitine. This protein
structure is made from two amino acids- lysine and methionine. Dr J.D.
Hulse and associates studied L-Carnitine in 1978 and found that vitamin
B-6 and Niacin were required in order to form it, as well as magnesium
and vitamin C in large amount. The lack of vitamin C in scurvy results
in high levels of blood fat, and this may be due to the body's inability
to produce carnitine. However, Dr. P. R. Borum discovered in 1981 that
not everyone has the same ability to manufacture this amino acid substance.
He found that some individuals have such a limited ability to produce
carnitine that this predisposes them to developing high blood fats and
cardiovascular problems. carnitine is found in its largest quantities
in the heart, liver, testes, and muscles. In the cells of these tissues
it combines with free fatty acids to form fatty acyl carnitine. In 1983
Dr. Borum found that carnitine is absolutely essential for the transportation
of fatty acids across the membrane and into the mitochondria. These
are energy producing factories of the cell. These are energy factories
of cell.
There these fatty acids
oxidized (burned) to release energy. As Dr. Hans Neiper has pointed
out, the heart muscles obtain more than half of its energy by burning
fatty acids, while skeletal muscle depends almost entirely on glucose.
Thus, a deficiency of carnitine greatly reduces the primary source of
energy for the heart. Such a deficiency can rapidly lead to angina
and cardiac insufficiency. In 1977 Dr. J. Bremer found that when carnitine
was deficient in the heart, fatty acids began accumulating in heart
cells, then the heart tissues and finally they backed into the blood.
This raised the blood levels
of triglycerides and cholesterol. The following year Dr. J.D. Folts
and teams found that when fatty acids remained in cardiac cells and
tissues because of a lack of carnitine to transport it into the mitochondria,
the fatty acids developed oxidative derivatives which became extremely
damaging to the heart muscle cells. Dr. M. Baroldi,a phologist who
worked with famous heart surgeon Dr. Dention Cooley and the U.S. Army
Pathological Institute in Washington, DC, has collected a large amount
of evidence that shows most heart attacks occur not because of blocked
arteries, but because heart muscles have developed abnormal chemistry
and die -thus leading to heart attack and death. Thus carnitine supplements
which improve heart muscles cell chemistry would seem to be a major
step forward in reversing this degeneration and death of heart muscle
cells, thus preventing heart attacks. As far back as 1975 Drs. J.D.McGarry
and W.D. Foster were giving cardiac patients supplements of carnitine.
They found that fat metabolism was increased and that triglycerides
and cholesterol levels fell dramatically. The following year Dr.
J.H. Thomsen and associates gave carnitine supplements to cardiac patients
and found that it improved the ability of the heart to withstand
stress tests. That same year Dr. Maebashi and team reported in the
Lancet that 8 weeks of carnitine supplements dropped the triglyceride
levels of a cardiac patient from 840 to 186%. In 1982 Drs. Rossi ans
Siliprandi found that carditine supplements significantly elevated the
protective HDL level. Dr. P. Pola and associate selected two groups
of patients, one group with high triglycerides, and one with high cholesterol.
They gave them supplements of carnitine for 40 days. Both groups
had dramatic declines in both their triglycerides and their cholesterol.
The data presented here makes it obvious that carnitine is a nutrient
which is very important in the body's ability to metabolize fats, particular
in the heart muscle cells. L-Carnitine is a very expensive supplement,
and its inclusion in the formula at a clinically effective levels of
750 mg. per day make this formula the most nutritionally supportive
formula for healthy cardiovascular tissue yet developed.
NUTRIENTS WORKING TOGETHER
We have just reviewed the scientific evidence which shows that each
of these nutrients is indvidually capable of helping the body raise
the benificial HDL and lowering the triglycerides. These nutrients are:
All of these beneficial
nutrients have been included in the "Lifetime" Formula at clinically
effective levels. In this way they can work synergistically together,
supporting and reinforcing each other - thus greatly amplifying their
powerful nutritional benifits.
B.
ELIMINATING PLAQUE AND ATHEROSCLEROSIS
DANEROUS FREE RADICALS
Most of the molecules in our body and natural foods are either electronically
balanced or carry ionic charge which allows them to join constructively
withother molecules. This is the basis for biochemistry that makes life
possible. However, most of the chemicals which are forien to our body
and our food readily break into molecules which carry a dangerous
and damaging electronical charge. These molecules are called
"free radicals."Prior to the year 1900, the average American had
very little exposure to chemicals in their food, water, or environment
which would break into free radicals. Americans also had almost no heart
attacks prior to 1900. Today there are over 3,000 chemicals being added
to our food as flavors, colors, emulsifiers, extenders, preservatives,
ect. Each of these is a potential free radiacal. Not to mention
chlorine and fluorine which has been added to our water supply, both
of which are sources of powerful free radicals. In his book, Coronaries-Cholesterol-Chlorine,
Dr. Joseph Price has pointed out the close relationship in the rise
of chlorinated water to rise in heart attacks.
NATURAL PROTECTION
People on a simple natural diet generally get all the nutrients they
need to control their biochemistryand live long and fruitful lives.
Their body is equippedwith enough of a special group of enzymes to neutralize
free radicals as they develop. However, on today's diet high in refined
and processed foods, loaded with chemicals and depleted of many key
nutrients, it is a different story. Free radicals released in the body
at such a high rate, and at such an early age, the body's ability to
control all of them is soon depleted, and much damage begins to occur.
HOW A PLAQUE FORMS
In 1973 Dr. Earl P. Benditt and associates at the University of Washington
School of Medicine discovered how arterial plaques form. They found
that when free radical molecules come in contact with cells that line
the inside of the artery, they damage the cell wall. later other free
radicals enter through this damaged area to the inner partsof the cell
where they cause additional damage. Eventually the cell is so altered
it becomes abnormal and begins to divide and multiply rapidly.
These plaque cells are largly
collagen which makes them very though. As the inner cells of this plaque
begin to grow old and degenerate, they yeild an above-average amount
of cholesterol. These cells also have an abnormal energy metabolism.
Dr. Benditt and team found that these plaque cells are very similar
to tumor cells. While this whole process has been going on, these plaque
cells have been releasing a prostaglandin called thromboxane or PG2.
This causes fibers to form over the top of the plaque, resulting
in red blood cells and platelets adhering to the plaque. Even
20 year old men were found to have thousands of tiny plaques forming
in their arteries when autopsies were performing during the Vietnam
war. Older people often have their arteries totally by these tough,
fibrous, cholesterol-laden plaques. This conditions is known as atherosclerosis.
NUTRIENTS TO PREVENT
ATHEROSCLEROSIS
Seven nutrients have been found to be very effective at neutralizing
free radicals before they can cause harm in the body. Supplements of
these nutrients have been able to halt free radical activity and prevent
plaque formation. The forthcoming research data will reveal the role
of some of these nutrients in body chemistry that prevents atherosclerosis.
custom essay service VITAMIN E
At the University of California, Davis, Dr. A.L. Tappel has established
that as an oil-soluble vitamin, vitamin E becomes part of the lipid
matrix in the cell wall, and prevents free radicals from burning holes
in it. Since the first step in the development of plaque and atherosclerosis
is created by the free radical attack of our arterial lining, vitamin
E's prevention of this is very important to us. At the University
of Puget Sound, Dr. J. Bland found that when exposed to free radicals
of ultra violet light and air, the walls of red blood cells broke
down. Within 13 hours 100% of the red blood cells had totally disintegrated.
Yet when these same volunteers supplemented their diet with Vitamin
E, only 5% of their red blood cells had disintegrated after exposure
to the same free radicals. It will be recalled that arterial plaque
cells are developed after free radical attack and are very much like
cancer cells. Dr. Denham Harman, University of Nebraska School of
Medicine, conducted an experiment in which he exposed the skin of
mice to cancer-causing chemicals. Then he fed them various nutrients
to see which ones offered the greatest protection against the development
of abnormal cancer cells. He found that vitamin C gave 32% protection,
selenium 42%, but vitamin E gave a whopping 63% protection.
Vitamin E is also found in heavy concentration
in the wall of mitochondria where energy is manufactured in the cell.
Without adequate vitamin E, oxygen escapes during the energy-releasing
process. This increases the body's need for oxygen. Drs. Houchin and
Mattill were able to demonstrate this by measuring muscle tissue's
oxygen requirements before and after supplementation with vitamin
E.
They found that within 24 hours
after vitamin E supplements, the oxygen requirement dropped by 60
to 71%. Imagine what this would mean to an oxygen-starved heart.
In 1963 Dr. Boyd and co-workers took X-rays of the arteries of people
with long standing atherosclerosis, before, during, and after supplementation
with vitamin E. The X-rays clearly showed the gradual clearing
of calcium and the dilation of the arteries over a period of a few
months. In 1968 Dr. Kurk Haeger did a controlled double blind
study of people with restricted blood flow due to narrow atherosclerotic
arteries.
After a few months, those on the placebo
showed a continued deterioration of their blood flow. Those on the
vitamin E showed a dramtic increase in their blood flow as measured
by objective scientific instruments. In 1980, Dr. J.L.Machlin established
that a large amount of published and confirmed scientific research
had proven vitamin E supplements will definitely prevent and reverse
atherosclerotic plaque, and evenup atherosclerotic narrowed
arteries over a period of months. Rabbits are highly prone to
develop high cholesterol and plaques when fed a fatty diet.
However, Drs. Wilson, Middleton, and
Sun found that when rabbits on this atherogenic diet were also given
vitamin E supplements, they were protected from free radical damage
and did not develop atherosclerotic plaques. Drs. Cheraskin and
Ringsdorf at the University of Alabama School of Medicine and Dentistry,
studied a group of middle aged male heart attack victims for a period
of one year. They found that those in the group who had a below average
intake of vitamin E had a deterioration of their condition comparable
to what is considered average for their age and condition.
However, those who were on vitamin
E supplements, and had an average intake, experienced a 30% reduction
in the severity of their condition. From thses studies we can
easily conclude that vitamin E is very important in reversing atherosclerotic
plaque formation and in protecting our body from the free radical
attack.
SELENIUM
Science has shown us that this little known element may very well be
the most important mineral to health of the heart and vascular system.
A powerful free radical scavenger in its own right, it also serves as
the heart of glutathione peroxidase, one of the two most important enzymes
our body uses to control free radicals. Dr. J.T. Rotruck did a study
on animal tissue levels of both selenium and the enzyme glutathione
peroxidase. He found the lower selenium levels were, the lower were
the levels of this all important enzyme. Dr. A.M. Novi has conducted
many experiment which have shown that when selenium-activated glutathione
is low, free radical damage to cell is massive, and leads to
the development of cancer cells- such as those that make up plaque
in their arteries.
The impact of a lack of
selenium on the blood vessels was noticed among animals where it has
been found to produce abnormalities in virtually evey specie, from chicken
and turkey, through swine, lambs, and cattle. It was estimated by the
U.S. Dept. of Agriculture that American farmers lost over 100 million
dollars in 1973 due to selenium deficiencies on the health of farm animals.
Drs. Schaamberger and C. Willis found that those between the ages of
55 and 64 living in selenium rich areas were protected with a heart
disease rate of 67% BELOW the national average, while those living
in selenium poor areas had a heart disease rate of 22% ABOVE
the national average. Dr. J.E. Vincent at Erasmus University, Rotterdam,
Netherlands is a world recognized authority on prostaglandins which
regulate the blood pressure. Their manufacture is dependent upon the
availability of selenium. He found that when selenium is low, these
prostaglandins will only be manufactured up to a certain point, then
as incomplete substances they willenter the blood stream.
These incomplete prostaglandins
now cause degenerative lesions, plaque formation platelet clumping,
and an elevation of blood pressure. Dr. James Aiken of the Upjohn
Laboratotie has discovered a kidney prostaglandin which regulates blood
pressure. Dr. N. Larsen in Vienn, Austria confirmed this discovery and
found, like Dr. Vincent in the Netherlands, that the production of this
prostaglandin is selenium dependant. He found that the blood from
patients with high blood pressure was always low in selenium compared
to the level of selenium in the blood of healthy people. Dr. Johan Borksten
studied the heart attack rate among the people of Finland and compared
it to the soil and water levels of selenium in the areas where they
lived.
He found that those who
lived in selenium richer areas had a heart attack rate of 1 per 1,730
people, while those living in low selenium areas had a heart attack
rate of 1 per every 224 people. A rather profound indictment of
the importance of selenium to the cardiovascular system. Another veryimportant
study on selenium was done in Finland. There a research team under the
direction of Dr. J. T. Salonen collected and froze the blood of 11,000
peolpe who had no outward sign of illness. All werethought to be healthy.
Over the next 10 years 367 of these people died from heart attacks or
other heart disease. They were carfully matched to other people from
this same group who still appeared to be healthy. They were matched,
according to age, sex, blood pressure, and cholesterol. The frozen blood
of all these peolpe was then thawed and compaed for differences. The
most glaring difference turened out to be the difference in their selenium
levels.
Those who developed fatal
heart conditions had much lower selenium levels in thier blood than
did those who remained healthy. It was also found that those who
had a selenium level below 45 mcg. per liter of blood, had a death rate
due to cardiovascular incidents 300% ABOVE those who had selenium levels
above 45 mcg. Including this examination of selenium, we should point
out that when selenium and vitamin E were mixed together in one tablet
and given to cardiac patients in Mexico City who had severe reoccurring
angina pectoris, Dr. J. Willalon reported that it was 92% effective
in eliminating or reducing angiana attacks and improved both the electrocardiogram
and the capacity of the patient to do work. All of this evidence
makes it more that just moderately clear that if we wish to have healthy
hearts, we must have an adequate daily intake of Vitamin E and Selenium.
ASCORBYL PALMITATE
Lipids (fats) when altered by free radicals become rancid. This happens
inside our body in the same way it does in our kitchen. Since the walls
of our cells, including arterial cells and red blood cells, are filled
with lipids, it is our great advantage to protect them. Tests by Eastman
Food Labratories have shown that soybean oi, a lipid like those in our
body, will become rancid in seven days when unprotected by a free radical
scavenger. The addition of just noe-tenth of one percent of vitamin
C as ascorbyl palminate will allow soybean oil to remain unaltered for
more than twice as long (16 days) before being altered by the free radicals.
Although very expensive, the "LIFETIME" formula contains a significant
amount of this powerful protector of lipids. in the blood stream ascorbyl
palminate may be able to protect the lipid-filled membranes of the arterial
cells from the plaque-generating free radicals with which they come
in contact, as readily as it protects soybean oil.
CHROMIUM
Chromium is another element that is important to the cardiovacular system.
Drs. Schroeder, Nason, and Tipton did a study on chromium and found
that when man or animals were deficient, there is a higher rate of
atherosclerosis and death. A study completed in Israel in 1980 by
Drs. A.S.Abraham and coworkers found that when rabbits develop clogged
arteries due to a high fat diet, chromium will allow these occlusions
to be dissolved. A study completed in 1978 by Dr. H.A. Newman and associates
found that patients reporting to hospitals with coronary artery disease
had chromium levels in thier blood serum several time lower
than those who reported for other conditions. In 1984 this study was
repeated by Dr. M. Simonoff and team, this time using blood plasma instead
of serum. It was again discovered that coronary patients had chromium
levels several times lower than non-coronary patients. These facts
definetly indicate that chromium deficiency plays a major role in the
generation of atherosclerosis.
VITAMIN C
We have previously mentioned the tremendous benefits of Vitamin C in
its role of raising the beneficial HDL and lowering the harmful LDL
cholesterol. However, vitamin C offers additional benefits to the cardiovascular
system by aslo acting as a neutralizer of free radicals before they
can attack our arteries creating atherosclerosis. In 1972 Dr. M.L. Riccitelli
of the Yale School of Medicine states that evidence has existed since
1949 that vitamin C will prevent atherosclerosis. He cited the work
of Dr. J. B. Duguid in 1949 that demonstraited the development of atherosclerosis
in guinea pigs simply by reducing their dietary intake of Vitamin C.
Researchers such as Dr. Emil Ginter of Czechoslovakia, Dr. G.C. Willis
of Canada, Dr. C.S. Leslie of England, Dr. K.R. Sebrov in Russia, and
in America R.O. Mummo at Rutgers University have all demonstrated
that when vitamin C levels are elevated, that not only does serum cholesterol
drop but that in both man and animals atherosclerotic plaques general
begin to disappear.
Using nothing but supplements
of Vitamin C, Drs. Krumdiek and Butterworkin 1974 obtained a substantial
reduction of plaque in 60%of the patients receiving the vitamin
C in less than a year, while none of the placebo group experienced plaque
reduction. Writing in the British Medical Journal, The Lancent, Dr.
E.G. Knox published the results of a study showing that high coronary
death rates in areas of England with low vitamin C intake, while areas
with high vitamin C intake had a much lower coronary death rate. Perhaps
one of the most amazing experiments by Dr. Sir Hans Krebs in England
in 1946 when he was able to induce heart attacks in healthy volunteers
between the ages of 20 and 30, simply by placing them on a diet dificient
in Vitamin C.
The importance of vitamin
C to a health cardiovascular system is born out by the research in Russia,
carried out by Dr. Zaitsev and coworkers in 1964. They fed radioactive
cholesterol to guinea pigs, then using a Geiger counter, determined
how there cholesterol was used. guinea pigs. Guinea pigs, like man,
require vitamin C in thier diet. Those not receiving enough vitamin
C deposited the cholesterol in their aora (the main artrey from the
heart). Whereas those who received adequate vitamin C deposited the
cholesterol in the liver, where with the use of vitamin C it was converted
to bile and excreated from the body, and in the adrenal glands, where
with the use of vitamin C it was coverted to hormones.
REVERSING ATHEROSCLEROSIS
While there is no nutrient which can either prevent or reverse plaque
formation or atherosclerosis, the human body can. It can, when it is
adequately supplied with the raw materials which allow it to do so.
Five of the most powerful raw materials to support the body in this
activity are Vitamin E, selenium, chromium, ascorbyyl palmitate, and
Vitamin C. These are the most powerful nutrients available for the protection
of the cardiovascular system against the damaging effects of free radicals
so prevalent in our modern world. Each of these is included in the "LIFETIME"
Formula at biologically effective levels where they are able to support
and reinforce each other.
In addition, they are supported
in the "LIFETIME" Formula by a full compliment of less active free radical
extinguishers- zink, copper, maganese, cystine, methionine, glutamine,
vitamin A, and beta-carotene. This entire cast of nutrients is able
to provide a basis of nutritional support to the cardiovascular system,
from which it may draw to protect itself from free radical degradation,
and thus maintain cardiovascular integrity, as well as provide broad
spectrum nutritional support for the entire body.
C.
PREVENTING CLOTS & THINNING THE BLOOD
PREVENTING STICKY BLOOD
The lining of the arteries is only one layer thick. Part of the duties
of thecells that make up this lining is the manufacture if a substance
known as prostaglandin 1, also called prostacyclin or PG1 for short.
Thsi substance keeps the walls of the arteries slippery so that
platelets and red blood cells do not stick to the artery walls, or to
each other. This is very important because as Dr. Maclouf and coworkers
have demonstrated, even a small clot releases thromboxane. This
is an inflammatory chemical that irritates the artery walls, stimulating
fibrinogen to create fibers, and causes other platlets and red
blood cells to become sticky and adhere to each other-thus promoting
atherosclerosis and blood clots, which may lead to strokes and heart
attacks. Obviously, it is important to prvent this. While the taking
of aspirin will thin the blood and prevent blood clots, it also creates
a toxic effect upon the liver, inhibits normal clottong of injuries,
and there is a danger of stomach hemorrhages. Just as effective at preventing
clots, but without the negative side effects, is a whole series of nutrients
which can also do a lot more for your body than just thin your blood
and prevent clots. we shall examine a few of these.
BROMELAIN
Bromelain is a complex of proteolytic enzymes found in the stem of green
pineapple. One of the amazing properties of bromelain is that unlike
other proteolytic enzymes, this one has the ability to cross the intestinal
wall and enter the blood stream. Several studies including one by Drs.
Miller and Oper show that up to 40% of orally ingested bromelain enters
the blood. Once in the blood, Drs. Ako and coworkers found that bromelain
activates a plasmin- a natural blood substance which dissolves the fibers
found in atherosclerotic plaques. In addition Drs. Schaffer and Adelman
found in 1985 that bromelain-activated plasmin prevents platelets from
abnormal clotting. This is achieved by inhibiting the production of
thromboxane-the irritating prostaglandin which causes blood clots. It
was found by Drs. Taussig and Nieper that a daily dose of 60 to 160mg.
of bromelain is sufficient to cleanse the arteries of blood clots when
given on a long-term basis. The "LIFETIME" Formula provides 200 mg.
per day, thus providing a nutritionally effective level.
GARLIC AND GINGER
As has been previously mentioned, free radical activation of thromboxane
leads to fiber formation, platelets aggregation, and clotting. All key
factors in the formation of atherosclerotic plaque. The herb garlic
contains a number of sulfur-rich compounds which Drs. Norwell
and Tarr found in 1983 inhibit an enzyme called cyclo-oxygenase.
It is this enzyme that is responsible for the release of damaging thromboxane.
By inhibiting this enzyme, garlic prevents the formation of atherosclerotic
fibers and clots. As dramatic as garlic is, the herb ginger is even
better. Ginger contains three different sesquiterpenes compounds
which Dr. K Sirvastava found in 1984 were significantly better at
inhititing thromboxane production and platelet clotting than was
garlic.
VITAMIN C AND E
It was found by Drs. Ross and Vogel in 1978 that vitamin C is capable
of preventing platelets from forming abnormal blood clots, while at
the same time not interfering with normal wound clotting time Dr. C.S.
Leslie conducted an experiment in which hospitalized clot-prone patients
were divided into two groups. One received a placebo and the other group
received one gram of vitamin C per day. A comparison demonstrated that
clot incidence among the vitamin C group was just half of the placebo
group. In 1949 Dr. Alton Ochsner, at the time a famous American
surgeon, discovered that by giving his surgical patients vitamin E supplements,
he could prevent the blood clots that usually follow surgery. During
the early 1970's a team of Swedish researchers led by dr. Korsn Bengsten
conducted four separate studies using vitamin E. In 1975 they
published their results showing that vitamin E made the blood thinner
and prevented abnormal blood clots, while not inhibiting normal
wound healing time. In 1981 a review of the research wound healing time.
In 1981 a review of the research showing vitamin E prevent abnormal
blood clots was verified and published by the highly respected New
England Journal of Medicine.
EPA-VITAMIN B-6 &
BIOFLAVONOIDS
In 1984 it was shown by a British research team led by Dr. B.E. Woodcock
that EPA found in marine lipids was capable of inhibiting the release
of thromboxane by promoting the syntheses of prostacycin. This allows
the platelets to remain slippery and prevents abnormal clotting of the
blood. Dr. S.C. Lam headed an American research team which discovered
that high blood levels of vitamin B-6 also inhibited platelets from
abnormal clotting. Dr. R.C. Robins at the University of Florida
has conducted a number of experiments comparing various bioflavonoid
compounds to the known anti-adhesive effect of powerful drug heparin.
This drug is usually injected in medical emergenceis to prevent blood
clots. Yet Dr. Robins found that the citrus bioflavonoids had superior
anti-thrombic ability to prevent clots that heparin. Dr. Robbins
has also made another amazing discovery with regard to bioflavonoids.
They lower elevated hematocrit to normal without lowering a normal one.
The hematocrit is the amount of red blood cells compared to the overall
blood volume. It was the famous Framinham Study that established a
high hematocrit as an indicator of impending heart attack or stroke.
However, the daily intake of bioflavonoids can lower the hematocrit
to normal. 96
Anti-Clotting Synergy
We have reviewed the scientific
finding on eight totally natural substances which reveals each of them
has the ability to dramatically inhibit platelets and red blood cells
from forming abnormal clots. An ability that exceeds even that of the
most potent anti-clotting drugs. Not only is this important from
the standpoint of preventing sudden death due to heart attacks, strokes,
and embolisms, it is also important from the standpoint of preventing
plaques and artherosclerosis. In 1978 it was found by Drs Ross and
Vogel that when platelets clump together they release a powerful mitogenic
polypeptide. The polypeptide causes DNA synthesis and the proliferation
of any cell where the platelets adhere along the arterial walls. 73
Thus the clots become extremely atherosclerogenic.
The eight natural substance reviewed here help the body prevent this
in a totally natural and beneficial way. With all eight of them working
together at a nutritionally effective level, such an unprecedented beneficial
effects is compounded by the synergy of reinforcement to reach an unprecedented
level of support for both the cardiovascular system, as well as the
entire human body an a maintenance basis.
Supporting
the Cardiovascular System
The following nutrients
in the "LIFETIME" Formula have all been found to provide specific nutritional
support for the cardiovascular system.
Vitamin A Supplements
have been found to be highly beneficial in the prevention of heart disease.
Drs Ross and Campbell conducted an experiment in which 136 patients
were given 24,000 IU of vitamin A and 3,000 IU of vitamin D per day.
Another 271 patients received only a placebo. At the end of 5-12
years, only 8 people of the 136 receiving the A & D supplements
developed coronary heart disease, while 43 of the 271 without the supplement
became afflicted. The incidence of heart disease without vitamin
A & D was 25 % greater than those who received it.83
Beta Carotene is a
very active single-oxygen quencher and a good free radical scavenger,
which prevent lipid peroxidation (Fat rancidity). Dr. J. A. Olson discovered
it is transported through the blood in LDL cholesterol where it helps
reduce its harmful oxidative effects on the arterial walls.84
THIAMIN - the first
member of the B-complex family has been found to be a vitally important
nutrient to the heart. Numerous animal experiments have demonstrated
this relationship. One study consisted of a thiamin analysis of cardiac
tissue from 10 people who died from heart attacks and 10 who had died
due to other causes. The thiamin content of heart attack victims
averaged 45% of that of non-heart attack victims.85
Ribofalvin- the second
B-vitamin was found in 1981 at the University of Alabama School of Medicine
to be vitally critical for the production of glutathione, one of the
two most important free radical controlling enzymes manufactured by
the body. Glutathione guards the lining of the blood vessels, the red
blood cells, and the lens of the eye from free radical attack. Drs.
Skalka and Prchal found that when riboflavin becomes to low, cataracts
form in the eye, red blood cells disintegrate, and arterial plaques
form rapidly.86
PANTOTHRNIC ACID-(B-5)
is known as the "stress vitamin" because of its role in supporting the
adrenal glands in producing stress hormones. It is also major component
of the important molecule C0enzyme A, which is vital to the creation
of energy from carbohydrates and fats. A lack of pantothenic acid
had been shown to lead to a rapid heart beat. 87
FOLIC ACID is a little
known vitamin important in a wide variety of functions, which is often
deficient in many people. Dr. T.L. Kopjas did a study with 17 elderly
patients with serve atherosclerosis. Giving them supplements of folic
acid, their small arteries dilated enabling blood to flow. Their
circulation so improved that vision improved and leg ulcers healed.88
BIOTIN is a vitamin
involved in energy pathways and lipid metabolism. The very physically
active and the elderly frequently demonstrate deficiencies. The Medical
Journal Artery reported in 1980 that supplements of this vitamin
to the elderly resulted in a decline of their elevated blood lipids.
89
PABA is a vitamin
best known for its ability to protect proteins from cross-linking, and
therefore a favorite sun-screen. However, in the 1977 Dr. B. Vessby
at the University of Uppsala in Sweden gave PABA supplement in a double-blind
cross-over study to individuals with elevated cholesterol. The PABA
lowered both cholesterol and triglycerides without lowering HDL.90
CHONDROITIN SULFATE a
& MUCOPOLYSACCARIDES - Dr. A. Verlangieri at Rutgers University
discovered that when atherosclerosis developed, something was lost from
the arterial wall. He found that cholesterol attached itself only to
those areas where the substance was missing. He learned that the
missing substance was Chondroitin Sulfate, which disappears when
vitamin C gets low. Meanwhile, Dr. L. Morrison began giving atherosclerotic
patients supplements of Chondroitin Sulfate extracted from calf trachea.
Dr. Morrison reported an 80% decline in the death rate of cardiac
patients receiving the supplement. 91
Chondroitin Sulfate is a mucopolysaccharide. Many mucopolysaccharide.
Normally circulate in the blood and have been found to lower cholesterol
and to retard the aging and degenerating of the arteries.92
Coenzyme Q-10 has
just recently been made available in the U.S. after having been used
in Japan for many years. However, it is an American, Dr. Karl Folkers
of Texas, who has completed such massive research on this natural body
enzyme. Studies have shown this vital energy-producing enzyme is
often deficient in cardiac patients. 93
Co Q-10 has been found to bring improvement in all forms of cardiac
malfunctions when taken in large enough doses on a daily basis. 94
DONG QUAI is an herb
which grows throughout most of the world. However, it is in Asia that
it has long been used for health purposes. Recent studies have shown
that this herb contains various forms of natural coumarins, which
create a vasodilating effect, which lowers blood pressure. This is achieved
through its calcium-blocking abilities. It has also been found to have
anti-arrhythmia characteristics. 95
HAWTHOREN BERRY is
an herb which for more than 100 years has been used as an extremely
effective support for the heart. It was said to relieve high blood pressure,
edema, poor valve function, rapid and irregular heart beat, and lung
congestion after all else had failed - and never once did it do harm
no mater how much was taken. All of these statements were made 75
years ago in the Journal of the AMA.97
GERMANIUM SESQUIODISE:
In use for the past several years in Japan, this organically-bounded
mineral carries three atoms of oxygen, which can be released in the
tissues. Drs. S. Tomizawa and associates reported in 1978 on research
which demonstrated the germanium compounds have the ability to lower
blood pressure and increase cardiac efficiency. 102
CONCLUSION:
One hundred two scientific
references have been cited in reviewing the key nutrients used in the
"LIFETIME" Formula. They clearly indicated that nutritional supplements
often can play a major role in creating a healthy heart and vascular
system - even after year of neglect. Just think, each of the results
cited here was obtained when only one nutrient was used! Imagine what
might be possible when all of them are used in one carefully balanced
formula!
"LIFETIME"
FORMULA AS A DAILY MAINTENCE. This Formula also offers a powerful
blend of synergistic nutrients carefully balanced to provide optimum
daily nutritional support, thus creating the ideal daily maintenance
supplement for exceptional health and longevity for people of all
ages!
WARNING: No one should
ever quit taking reduce heart or blood pressure medication unless being
advised to do so by their physician. To do otherwise could be fatal.
Some medications are easy to get on, but very difficult to get off.